モノクローナル抗ビンキュリン抗体 マウス宿主抗体

モノクローナル抗ビンキュリン抗体 マウス宿主抗体 価格

モノクローナル抗ビンキュリン抗体 マウス宿主抗体 化学特性,用途語,生産方法

• 使用

  Anti-vinculin antibody produced in rabbit has been used in following studies:
  
  • immunofluorescence
  • immuno-histology
  • western blotting

• 一般的な説明

  Monoclonal Anti-Vinculin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

• Biochem/physiol Actions

  Vinculin (VCL) is a cytoskeletal protein, which plays a vital role in regulation of cell-to-cell and cell to matrix junctions. VCL facilitates normal embryonic development and cardiac function. Aberration or mutation of the gene leads to cardiomyopathy. VCL also plays a crucial role in cell migration and morphogenesis. VCL might facilitate the binding of integrins and cadherins to the actin cytoskeleton. Vinculin plays an important role in integrin αIIbβ3 signaling and function, which is required for platelet aggregation.

モノクローナル抗ビンキュリン抗体 マウス宿主抗体 生産企業

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