4-(ソジオオキシ)安息香酸プロピル

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H318：重篤な眼の損傷

• 注意書き

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

4-(ソジオオキシ)安息香酸プロピル 価格

4-(ソジオオキシ)安息香酸プロピル 化学特性,用途語,生産方法

• 定義

  本品は、プロピルパラベン(*)のナトリウム塩であり、次の化学式で表される。
  参照表示名称：プロピルパラベン

• 化粧品の成分用途

  防腐剤

• 効能

  抗菌性保存剤

• 化学的特性

  White or almost white, hygroscopic, crystalline powder.

• 使用

  Sodium Propylparaben is a preservative. Sodium Propylparaben is also an excipient used in various pharmaceutical formulations.

• 調製方法

  Propylparaben sodium is produced from benzoic acid.

• 応用例（製薬）

  Propylparaben sodium is used as an antimicrobial or antifungal preservative in oral pharmaceuticals and in many water-based cosmetics. It is generally used in combination with other paraben esters.

• 接触アレルゲン

  This substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.

• 安全性

  Propylparaben sodium is used in oral pharmaceuticals and cosmetics. The pure form is toxic by the IV route and moderately toxic by ingestion and the IP route. Propylparaben sodium may cause asthma, rashes, and hyperactivity.
  LD50 (mouse, IP): 0.49 g/kg
  LD50 (mouse, IV): 0.18 g/kg
  LD50 (mouse, oral): 3.7 g/kg

• 貯蔵

  Propylparaben sodium is stable under normal conditions. It decomposes on heating. Store in a tightly closed container.

• 不和合性

  The activity of propylparaben sodium can be adversely affected by the presence of other excipients or active ingredients, such as atropine, essential oils, iron, magnesium trisilicate, talc, polysorbate 80 and other nonionic surfactants, sorbitol, weak alkalis, and strong acids.

• 規制状況(Regulatory Status)

  Included in the FDA Inactive Ingredients Database (oral capsules, tablets, suspensions). Accepted for use as a food additive in Europe. Included in nonparenteral medicines (oral capsules, mixtures, orodispersible tablets, solutions and suspensions; cutaneous emulsions) licensed in the UK.

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