Dornase alpha (Pulmozyme) is ahighly purified solution of recombinant human deoxyribonucleaseI (rhDNAse). It is indicated for use in cystic fibrosisbecause of its ability to liquefy secretions from thelung effectively. It accomplishes this by cleaving the extracellularDNA in purulent sputum and reducing the viscosityand elasticity of the secretion.
