Phytohemagglutinin-M (PHA-M) has been used in the activation of Jurkat and primary cells. It has also been used to treat polymorphonuclear blood cells(PMBCs)
一般的な説明
Lectins are distinct proteins or glycoproteins that have at least one non-catalytic domain which fixes reversibly to a definite mono- or oligosaccharide. Some of their potentially utilizable biological assets include: antitumor, immunomodulatory and anti-insect, antifungal, antibacterial, anti-HIV, and mitogenic properties.
Biochem/physiol Actions
Phytohemagglutinin (PHA) has mitogenic and potent cell agglutinating activities. It binds to T-cell membranes and stimulates cell division and metabolic activity. PHA has the ability to stimulate close contacts between cell membranes.
