モノクローナル抗カルシトニン遺伝子関連ペプチド抗体 マウス宿主抗体

モノクローナル抗カルシトニン遺伝子関連ペプチド抗体 マウス宿主抗体 価格

モノクローナル抗カルシトニン遺伝子関連ペプチド抗体 マウス宿主抗体 化学特性,用途語,生産方法

• 使用

  Anti-Calcitonin Gene-Related Peptide (CGRP) antibody is suitable for immunohistochemistry at a working antibody dilution of 1:200 to 1:1000 using formalin-fixed, paraffin-embedded sections or cryostat tissue sections. The antibody may be used for immunofluorescence at a working dilution of 1:500.

• 一般的な説明

  Calcitonin Gene Related Peptide (CGRP), a cyclic peptide, belongs to a small family of peptides encoded by the calcitonin/CGRP gene complex. The calcitonin/CGRP gene complex consists of at least two genes, encoding for two forms of CGRP: -CGRP (CGRP-I) and -CGRP (CGRP-II). CGRP is synthesized and co-localized with calcitonin in the parafollicular C-cells of the thyroid gland and medullary thyroid carcinoma. It is principally considered a neuropeptide widely distributed in the central and peripheral nervous systems.

• Biochem/physiol Actions

  CGRP is thought to act as a neurotransmitter or neuromodulator, particularly in the regulation of autonomic (e.g., cardiovascular, respiratory, gastrointestinal, taste, food intake and sleep) and limbic functions. CGRP is probably involved with substance P in mediating neurogenic inflammation and transmission of pain stimuli via the peripheral nervous system.

モノクローナル抗カルシトニン遺伝子関連ペプチド抗体 マウス宿主抗体 生産企業

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