抗DAPキナーゼ1抗体 ウサギ宿主抗体

抗DAPキナーゼ1抗体 ウサギ宿主抗体 化学特性,用途語,生産方法

• 使用

  Anti-DAP Kinase 1 antibody is suitable for use in immunoprecipitation (2.5-5.0 μg using extracts of human HeLa cells) and western blot (1-2 μg/mL using whole extracts of human HeLa cells).

• 一般的な説明

  DAP-kinase 1 is a Ca²⁺/calmodulin dependent Ser/Thr kinase that associates with microfilaments. The protein is composed of a multidomain structure. It has a subdomain typical of serine/threonine kinases, a Ca²⁺/calmodulin regulatory domain, eight ankyrin repeats followed by two P-loop motifs and a typical death domain module. It contains two auto-inhibitory domains, one being Ca²⁺/calmodulin dependent.

• Biochem/physiol Actions

  Death-associated protein kinase (DAPK) belongs to the serine/threonine kinase family that regulates apoptosis, growth factor signaling and also may be involved in modulating immune responses. DAPK1 mediates cellular functions such as membrane blebbing and autophagy and inhibits the activity of prolyl isomerase

抗DAPキナーゼ1抗体 ウサギ宿主抗体 生産企業

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