DL-エチオニン

化学名:DL-エチオニン

CAS番号.67-21-0

英語名:DL-ETHIONINE

CBNumberCB6165509

MFC6H13NO2S

MW163.24

别名

DL-エチオニン

rac-(R*)-2-アミノ-4-(エチルチオ)酪酸

rac-(R*)-2-アミノ-4-(エチルチオ)ブタン酸

DL-エチオニン物理性質

安全性情報

主な危険性	Xi
Rフレーズ	36/37/38
Sフレーズ	26
WGK Germany	3
RTECS 番号	ES6825200
TSCA	Yes
HSコード	29309090
毒性	The Sethyl analog of methionine. It is a carcinogen and hepatotoxic agent once proposed as an antineoplastic agent. It inhibits the incorporation of methionine and glycine into proteins and substitutes for methionine in transmethylation reactions, the ethyl group appearing in the products in place of the methyl groups of methionine (e.g., ethylcholine is formed instead of choline). Ethionine is currently used only as an experimental compound in studies of hepatotoxicity and methionine metabolism and nutrition.

危険有害性情報のコード(GHS)

外観
白色～ほとんど白色, 結晶～結晶性粉末
溶解性
うすい塩酸に溶けやすく、水に溶け、エタノールに溶けにくい。
用途
生化学研究用。アミノ酸研究用。
化学的特性
Off-White Solid
使用
DL-Ethionine is used as a dietary supplement to accelerate cholangiocarcinogenesis in vivo. It is also used to induce oxidative stress in liver to study the levels and activities of anti-oxidative enzymes and compounds such as glutathione.
定義
ChEBI: A non-proteinogenic alpha-amino acid that is methionine in which the S-methyl group is replaced by an S-ethyl group.
一般的な説明
White crystalline flakes.
空気と水の反応
Slightly soluble in water.
反応プロフィール
A synthetic thio-substituted amino acid.
健康ハザード
ACUTE/CHRONIC HAZARDS: When heated to decomposition DL-ETHIONINE emits toxic fumes of NOx and SOx.
火災危険
Flash point data for DL-ETHIONINE are not available; however, DL-ETHIONINE is probably combustible.
安全性プロファイル
Mddly toxic by ingestion and intraperitoneal routes. Suspected carcinogen with experimental carcinogenic and tumorigenic data. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.