ANTI-RECEPTOR INTERACTING PROTEIN

ANTI-RECEPTOR INTERACTING PROTEIN 価格

ANTI-RECEPTOR INTERACTING PROTEIN 化学特性,用途語,生産方法

• 使用

  Anti-RIPK1 antibody produced in rabbit has been used in:
  
  • western blotting
  • immunocytochemistry
  • immunofluorescence
  
  

• 一般的な説明

  Receptor interacting serine/threonine kinase 1 (RIPK1) gene is located at 6p25.2 on the human chromosome. It belongs to the RIPK family. RIPK1 is a necroptosis regulatory protein. It is made up of N-terminal kinase domain, a RIP homotypic interaction motif and its C-terminal contains the death domain.

• Biochem/physiol Actions

  Receptor interacting serine/threonine kinase 1 (RIPK1) is involved in inflammatory signaling and prosurvival. It is also involved in regulating the caspase-8-mediatedapoptosis. RIPK1 plays a role in activating nuclear factor kappa-light-chain-enhancer of activated B cells(NF-κB)andmitogen-activated protein (MAP) kinases. Mutations in this gene is associated with impaired innate and adaptive immunity. It also leads to very early onset inflammatory bowel diseases (VEO-IBDs).

ANTI-RECEPTOR INTERACTING PROTEIN 生産企業

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