(8aα)-オクタヒドロインドリジン

(8aα)-オクタヒドロインドリジン 化学特性,用途語,生産方法

• 化学的特性

  Colorless liquid with characteristic odor sim ilar to coniine; boils at 171°C (339.8°F); density 0.875 at 15°C (59°F); alkaline; slightlysoluble in water, dissolves readily in organicsolvents.

• 使用

  γ-Coniceine occurs in the seeds of poisonhemlock (Conium maculatum L. or Umbelliferae). It is produced by reduction ofconiine.

• 健康ハザード

  Acute oral toxicity of γ-coniceine is greaterthan that of coniine. The symptoms are similar. Ingestion may cause drowsiness, nausea,vomiting, respiratory distress, convulsions,cyanosis, and at high doses, death. An oralLD50 value in mice is reported as 12 mg/kg(NIOSH 1986).