チオりん酸O,O-ジメチルS-(N-メチルカルバモイルメチル)

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H300：飲み込むと生命に危険

  H311：皮膚に接触すると有毒

  H400：水生生物に強い毒性

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P273：環境への放出を避けること。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P301+P310：飲み込んだ場合：直ちに医師に連絡すること。

チオりん酸O,O-ジメチルS-(N-メチルカルバモイルメチル) 価格

MSDS Information

• O,O-Dimethyl S-methylcarbamoylmethyl phosphorothioate

チオりん酸O,O-ジメチルS-(N-メチルカルバモイルメチル) 化学特性,用途語,生産方法

• 外観

  無色〜うすい黄色, 澄明の液体

• 溶解性

  水, アセトン, エタノールや多くの炭化水素と混和する。ジエチルエーテルや揮発油にわずかにとける。水、エタノール及びアセトンに溶ける。

• 農薬用途

  殺虫剤

• 使用上の注意

  アルゴン封入

• 使用

  Omethoate is a systemic insecticide used for the control of (mostly) sucking insects and mites in a wide variety of crops.

• 接触アレルゲン

  Contact dermatitis from omethoate-dimethoxon is rare.

• 代謝経路

  Omethoate is the P=O analogue (oxon) of dimethoate. Dimethoate is metabolised via oxidative desulfuration to omethoate which is the active anti-acetylcholinesterase metabolite. This biotransformation occurs in all media: hence the metabolic pathways of both compounds have much in common. However, degradative pathways acting directly on dimethoate such as O-demethylation, N-demethylation and hydrolysis of the amide function mean that the balance between activation and degradative metabolism will influence their respective selective toxicities. In mammals there are two main routes of degradation: (i) glutathione transferase mediated O-demethylation (ii) hydrolysis to N-methylthioglycolamide which is S-methylated by S-adenosylmethionine and subsequently thiooxidised. In soil and plants the N-methylthioglycolamide moiety formed from the hydrolysis of omethoate undergoes a complex series of C₁, C₂ and C₃ biotransformations ultimately leading to oxalate and citrate respectively and total degradation to C0₂. The information reported below is derived largely from an evaluation prepared by the UK MAFF Pesticide Safety Directorate (PSD, 1993).

• 代謝

  Orally administered omethoate to rats is rapidly metabolized and excreted in the urine; the main metabolites are O-demethylomethoate and N-methyl-2- methylsulfinylacetamide. O-Demethylation and hydrolysis of the P?S bond are main degradation routes both in mammals and plants. Omethoate is rapidly degraded in soils with DT₅₀ of a few days.

チオりん酸O,O-ジメチルS-(N-メチルカルバモイルメチル) 上流と下流の製品情報

1113-02-6, チオりん酸O,O-ジメチルS-(N-メチルカルバモイルメチル) キーワード