ペニーロイヤルミント油

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H411：長期的影響により水生生物に毒性

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P301+P312：飲み込んだ場合：気分が悪い時は医師に連絡する こと。

  P330：口をすすぐこと。

  P501：内容物/容器を．．．に廃棄すること。

ペニーロイヤルミント油 化学特性,用途語,生産方法

• 定義

  本品は、ペニーロイヤルミント Mentha pulegium の全草から得られる精油である。

• 化粧品の成分用途

  香料

• 化学的特性

  American pennyroyal essential oil is obtained from H. pulegioides by steam distillation in approximately 0.6 to 1.0% yields. It is a pale-yellow liquid with a much harsher mint-like odor, more bitter and herbaceous than the European oil. The taste is sharp, bitter and slightly burning.

• 物理的性質

  It is a pale-yellow-to-yellow, aromatic oil.

• 天然物の起源

  Found in the plant Mentha pulegium L. (Fam. Labiatae).

• 使用

  Fragrance component in soaps, perfumes; flavoring agent; insect repellent.

• 製造方法

  By steam distillation of the fresh or partly dried plant Mentha pulegium L.

• 精油の成分

  Depending on the genus, the leaves and flowering tops yield 1 to 2% pennyroyal oil. The oil contains 80 to 96% of the cyclohexanone and pulegone. Other constituents of pennyroyal oil include methone, pinene, octanol, piperitenone, limonene, iso-methone and acetic, butyric, salicylic and other acids.

• 一般的な説明

  Pennyroyal (Hedeoma pulegeoides, Mentha pulegium) is an example of an extremely toxic herb. The plant is a member of the mint family, Labiatae. The dried leaves and flowering tops of the plant contain from 16% to 30% oil, consisting of the monoterpene pulegone. The oil also contains tannins, α- and β-pinenes, other terpenes, long-chain alcohols, piperitenones, and paraffin.
  The toxicity of pennyroyal is believed to be a result of the pulegone in the oil. Cytochrome P450 catalyzes the metabolism of pulegone to yield the toxic metabolite menthofuran. Possibly, some of the other terpenes undergo oxidation to active metabolites as well. Menthofuran, metabolites of other terpenes, and pulegone itself deplete hepatic glutathione, resulting in liver failure. This mechanistic hypothesis is supported by the fact that administration of acetylcysteine reverses the toxicity.
  Pennyroyal has been used as an abortifacient since the time of Pliny the Elder, an insect repellent (the terpenes in the oil have citronellal-like properties), an aid to induce menstruation, and a treatment for the symptoms of premenstrual syndrome. It has also been used as a flea repellent on dogs and cats. When used as an abortifacient, the drug often causes liver failure and hemorrhage, leading to death. Pennyroyal is sometimes used with black cohosh to accelerate the abortifacient effect. Coma and death have been reported. Pennyroyal is an example of an herb that has no safe uses.

ペニーロイヤルミント油 生産企業

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