抗ヒストン脱アセチル化酵素1(HDAC1)抗体 ウサギ宿主抗体

抗ヒストン脱アセチル化酵素1(HDAC1)抗体 ウサギ宿主抗体 価格

抗ヒストン脱アセチル化酵素1(HDAC1)抗体 ウサギ宿主抗体 化学特性,用途語,生産方法

• 使用

  Anti-Histone Deacetylase 1 (HDAC1) antibody has been used in immunohistochemical staining and chromatin immunoprecipitation (ChIP) analyses.

• 一般的な説明

  Histone acetylation is a dynamic process whose levels are determined by the net activities of HATs and the competing enzymes histone deacetylases (HDACs). Both activities are associated with the nuclear matrix. Six or seven different mammalian HDACs have been described. HDAC1, HDAC2 and HDAC3 are similar to yeast Rpd3 protein, while HDAC4, HDAC5 and HDAC6 are similar to yeast Hda1 protein. Histone deacetylases activities were often, but not always, associated with transcriptional repression and nucleosomal condensations. HDAC1, HDAC2 and several other HDACs are the catalytic subunits of different multiprotein regulatory complexes.

• Biochem/physiol Actions

  Histone deacetylase 1 (HDAC1) prevents the infection of influenza A virus (IAV). The protein plays important roles in DNA repair, splicing, regulation of gene expression and cell division. Overexpression of this gene can be seen in cancers like breast, renal cell cancer, and classical Hodgkin′s lymphoma.

抗ヒストン脱アセチル化酵素1(HDAC1)抗体 ウサギ宿主抗体 生産企業

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