1,3-ジオキソラン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H225：引火性の高い液体および蒸気

  H319：強い眼刺激

  H360：生殖能または胎児への悪影響のおそれ

• 注意書き

  P201：使用前に取扱説明書を入手すること。

  P210：熱/火花/裸火/高温のもののような着火源から遠ざ けること。－禁煙。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P308+P313：暴露または暴露の懸念がある場合：医師の診断/手当てを 受けること。

1,3-ジオキソラン 価格

MSDS Information

• Ethylene glycol methylene ether

1,3-ジオキソラン 化学特性,用途語,生産方法

• 外観

  無色～ほとんど無色, 澄明の液体

• 定義

  本品は、次の化学式で表される有機化合物である。

• 溶解性

  水, エタノール, アセトンに易溶。

• 解説

  C3H6O2(74.08)．1,3-ジオキソランは，エチレングリコールとパラホルムアルデヒドとを酸触媒の存在下に加熱反応させると得られる．融点－95 ℃，沸点75～76 ℃．d²⁰₄1.066．n²⁰_D1.397．水，エタノール，エーテル，アセトンに可溶．臭素水を脱色する．カチオン重合性があり，重合度2000以上のホモポリマーやトリオキサンと開環共重合して，安定なアセタール樹脂を与える．森北出版「化学辞典（第2版）

• 用途

  リチウム電池?コンデンサー溶媒、エンジニアリングプラスチック原料

• 化粧品の成分用途

  溶剤

• 化学的特性

  Colourless Liquid. Miscible with water, soluble in alcohol, ether and benzene. The azeotrope formed with water, the azeotrope is 70-73°C, and the water content is 6.7%. Decolorize bromine water.

• 使用

  1,3-Dioxolane is an intermediate for the preparation of Acyclovir (A192400). Also, 1,3-Dioxolane is used in the synthesis of new Vandetanib (V097100) analogs.

• 定義

  ChEBI: 1,3-dioxolane is a cyclic acetal that is pentane in which the carbon atoms at positions 1 and 3 are replaced by oxygen atoms respectively. It is a dioxolane and a cyclic acetal.

• 主な応用

  1,3-Dioxolane (DOXL) is a cyclic ether. It is a green solvent. It undergoes reaction with C60 to afford an epoxide and 1,3-dioxolane derivative. Reaction has been reported to proceed via a diradical mechanism. A mixture of tetra(ethylene glycol) dimethyl ether (TEGDME) and DOXL has been used to compose the binary electrolyte for use in lithium-sulfur battery. Its efficacy as a solvent in a non-aqueous redox flow battery system has been tested. 1,3-Dioxolane may be used in the fabrication of batteries and capacitors. It may be used as one of the co-solvent to prepare the electrolyte for lithium-sulfur batteries.

• 一般的な説明

  A clear colorless liquid. Flash point 35°F. Slightly denser than water. Vapors heavier than air.

• 空気と水の反応

  Highly flammable. When exposed to air 1,3-Dioxolane undergoes autooxidation with formation of peroxides. In the distillation process peroxides will concentrate causing violent explosion. Soluble in water.

• 反応プロフィール

  Ethers, such as 1,3-Dioxolane, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.

• 健康ハザード

  The acute inhalation and oral toxicity of1,3-dioxolane is low in test animals. Thevapor is irritant to eyes and respiratory tract.Application of the liquid produced severeirritation in rabbits’ eyes and mild action onthe animals’ skin. The information on thetoxicity of this compound in humans is notknown.
  The inhalation LC50 value of 4-hour exposurein rats is in the range of 20,000 mg/m³,and the oral LD50 is 3000 mg/kg (NIOSH1986).

• 火災危険

  HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

• 工業用途

  1,3-Dioxolane is used to dissolve a wide spectrum of polymeric materials such as acrylates, alkyds, cellulosics, epoxies, polycarbonates, polyesters, urethanes, and vinyl resins. In many cases, 1,3-dioxolane solvent can replace the chlorinated solvents that were used previously to dissolve many of these polymers. The excellent solvency of 1,3-dioxolane for polymeric compositions makes this cyclic ether a valuable component in paint remover formulations. 1,3-Dioxolane is used to treat polyester fibers for improved dye retention, application of cross-linking agents to cellulosic fibers, and bonding of acrylonitrile polymers. 1,3-Dioxolane is used in metal working and electroplating formulations, as a complexing solvent for organometallic and inorganic salts, and in the preparation of lithium battery electrolyte solutions. 1,3-Dioxolane is a valuable reactant in the polymerization reactions to produce polyacetals. Polymerization reactions of dioxolane with itself or with aldehydes and ethers are catalyzed by a Lewis acid to yield the polyacetal polymers. The methylene group (CH2) bonded to the two oxygen atoms in dioxolane is susceptible to radical abstraction of a hydrogen atom and the resultant dioxolane radical species can be added across various double bond configurations.

• 安全性プロファイル

  Moderately toxic by ingestion and intraperitoneal routes. Mildly toxic by skin contact and inhalation. A shin and severe eye irritant. Mutation data reported. A very dangerous fire hazard when exposed to heat or flame; can react with oxidizers. Used in lithium batteries. Potentially explosive reaction with lithium perchlorate. When heated to decomposition it emits acrid smoke and irritating fumes.

• 純化方法

  Dry it with solid NaOH, KOH or CaSO4, and distil it from sodium or sodium amalgam. Barker et al. [J Chem Soc 802 1959] heated 34mL of dioxalane under reflux with 3g of PbO2 for 2hours, then cooled and filtered. After adding xylene (40mL) and PbO2 (2g) to the filtrate, the mixture is fractionally distilled. Addition of xylene (20mL) and sodium wire to the main fraction (b 70-71o) led to a vigorous reaction, following which the mixture was again fractionally distilled. Xylene and sodium additions are made to the main fraction (b 73-74o) before it is finally distilled. [Beilstein 19/1 V 6.]

1,3-ジオキソラン 上流と下流の製品情報

1,3-ジオキソラン 生産企業

Global(394)Suppliers

1,3-ジオキソラン スペクトルデータ(¹HNMR、¹³CNMR、IR1、MS、Raman)

646-06-0, 1,3-ジオキソラン キーワード