ANTI-CDK4

ANTI-CDK4 価格

ANTI-CDK4 化学特性,用途語,生産方法

• 使用

  Monoclonal Anti-Cdk4 antibody was used in:
  
  • immunoprecipitation of human melanoma cell line.
  • immunofluorescence of fibrosarcoma cells.
  • western blot analysis
  • immunofluorescence
  • immunohistochemistry

• 一般的な説明

  Cdk4 exists, in part, as a multi-protein complex with a D-type cyclin, proliferating cell nuclear antigen (PCNA) and a protein inhibitor, p21^Cip1. Cdk4 associates separately with p16, particularly in cells lacking a functional retinoblastoma protein.

• Biochem/physiol Actions

  In association with cyclins, cyclin-dependent kinases (CDKs) forms active kinase complexes which is responsible for regulating cell cycle progression in eukaryotic cells. Within the complexes, the CDKs serves a catalytic protein kinase activity. This catalytic activity is regulated by two mechanisms: protein phosphorylation and association of regulatory subunits.

ANTI-CDK4 生産企業

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