L-N6-(1-イミノエチル)リジン 二塩酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

L-N6-(1-イミノエチル)リジン 二塩酸塩 価格

L-N6-(1-イミノエチル)リジン 二塩酸塩 化学特性,用途語,生産方法

• 説明

  L-NIL is a relatively selective inhibitor of iNOS. It exhibits IC₅₀ values of 0.4-3.3 μM for iNOS as opposed to 8-38 and 17-92 μM for eNOS and nNOS, respectively. L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major.

• 使用

  L-N⁶-(1-Iminoethyl)lysine dihydrochloride has been used as an inducible nitric oxide synthase (iNOS) inhibitor:
  
  • to study its effects on leptin-induced modulation of fibronectin type III domain-containing five (FNDC5)/irisin in myocytes and fat cells of murine
  • to study its effects on leptin-induced inflammation in hepatocytes
  • to block the production of nitric oxide in mice bone marrow mesenchymal stromal cells (BMSCs)
  
  

• Biochem/physiol Actions

  Selective inhibitor of inducible nitric oxide synthase (iNOS).

L-N6-(1-イミノエチル)リジン 二塩酸塩 生産企業

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