フシジン酸ナトリウム

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

フシジン酸ナトリウム 価格

フシジン酸ナトリウム 化学特性,用途語,生産方法

• 効能

  抗生物質, タンパク質合成阻害薬

• 商品名

  フシジンレオ (第一三共)

• 説明

  Fusidic acid is a fusidane antibiotic originally isolated from F. coccineum. It is active against the Gram-positive bacteria S. aureus, S. pyogenes, C. diphtheriae, B. subtilis, and C. tetani (MIC₅₀s = 0.01-20 μg/ml) but not the Gram-negative bacteria E. coli, S. typhimurium, and P. vulgaris or the fungi C. albicans and A. fumigatus (MIC₅₀s = >100 μg/ml for all). Fusidic acid inhibits ribosomal recycling and protein translocation, processes mediated by elongation factor G (EF-G), in isolated E. coli ribosomes (IC₅₀s = ~0.1 and ~200 μM, respectively). Topical administration of fusidic acid (2%) reduces the number of skin colony forming units (CFUs) and levels of TNF-α and IL-6 in a mouse model of methicillin-resistant S. aureus (MRSA) skin wound infection.

• 化学的特性

  White or almost white, crystalline powder, slightly hygroscopic.

• 使用

  Sodium fusidate is the more water soluble sodium salt of fusidic acid, a steriodal metabolite of Fusidum coccineum which is a potent Gram positive antibiotic. Fusidic acid inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Fusidic acid also suppresses NO lysis of pancreatic islet cells.

• 一般的な説明

  Fusidic acid is an antibiotic substance, resembling the structure of a steroid. It belongs to the class of fusidanes.

フシジン酸ナトリウム 生産企業

Global(355)Suppliers

フシジン酸ナトリウム スペクトルデータ(¹HNMR、FT-IR、IR、Raman)

751-94-0, フシジン酸ナトリウム キーワード