Ipecac syrup is prepared from the dried rhizome and
roots of Cephaelis ipecacuanha or Cephaelis acuminata,
plants from Brazil and Central America that have the
alkaloid emetine as their active principal ingredient. It
acts directly on the CTZ and also indirectly by irritating
the gastric mucosa.
危険性
Contains emetine, a toxic alkaloid.
作用機序
Ipecac is cardiotoxic if absorbed and
can cause cardiac conduction disturbances, atrial fibrillation,
or fatal myocarditis. If emesis does not occur,
gastric lavage using a nasogastric tube must be performed.