9-フルオロ-11β,21-ジヒドロキシ-16α,17-[2-プロペニリデンビス(オキシ)]プレグナ-1,4-ジエン-3,20-ジオン

9-フルオロ-11β,21-ジヒドロキシ-16α,17-[2-プロペニリデンビス(オキシ)]プレグナ-1,4-ジエン-3,20-ジオン 化学特性,用途語,生産方法

• Originator

  Acrocinonide ,Onbio Inc.

• Manufacturing Process

  A suspension of 1.0 g of 9-fluoro-11β,16α,17,21-tetra-hydroxy-pregna-1,4- diene-3,20-dione in a mixture of 35 ml of dioxan, 15 ml of acrolein and 0.1 ml of perchloric acid was stirred for 3 h at room temperature. The clear solution thus obtained was poured into an aqueous saturated solution of sodium bicarbonate. The mixture was extracted twice with benzene, and the benzenic extract was concentrated to a small volume. The resulting crystals were collected and the 9-fluoro-11β,21-dihydroxy-16α,17-(2-propenylidenedioxy)- pregna-1,4-diene-3,20-dione was obtained as white crystals, melting point 200°-205°C.

• Therapeutic Function

  Antiinflammatory, Antiallergic

9-フルオロ-11β,21-ジヒドロキシ-16α,17-[2-プロペニリデンビス(オキシ)]プレグナ-1,4-ジエン-3,20-ジオン 上流と下流の製品情報

9-フルオロ-11β,21-ジヒドロキシ-16α,17-[2-プロペニリデンビス(オキシ)]プレグナ-1,4-ジエン-3,20-ジオン 生産企業

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