プロアジフェン塩酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P330：口をすすぐこと。

プロアジフェン塩酸塩 価格

プロアジフェン塩酸塩 化学特性,用途語,生産方法

• 効能

  増強薬, シトクロムP450酵素阻害薬

• 説明

  SKF 525A is a widely used, nonspecific cytochrome P (CYP)450 inhibitor that demonstrates 100% inhibition of the various CYP450 isoforms at 1-100 μM. It therefore potentiates the effects of many different drugs by inhibiting their metabolism (IC₅₀ values in the μM range when tested using human liver microsomes). SKF 525A inhibits CYP450-dependent arachidonic acid conversion to active EET metabolites, antagonizing the recovery of functional calcium pools. It also acts as a noncompetitive inhibitor of acetylcholine nicotinic receptors (IC₅₀ = 19 μM in mouse skeletal muscle).

• 化学的特性

  Off-White Crystalline Solid

• 使用

  Proadifen hydrochloride is an inhibitor of NOS1, AChR, cytochrome P-450, and KIR6. Proadifen hydrochloride bind to the protein moiety of P-450, also reduced the hypoxic response. of Proadifen hydrochloride have good antiarrhythmic effects. SKF-525A substantially reduced the depletion of cardiac norepinephrine.

• 安全性プロファイル

  Poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and HCl.

プロアジフェン塩酸塩 生産企業

Global(114)Suppliers

プロアジフェン塩酸塩 スペクトルデータ(¹HNMR)

62-68-0, プロアジフェン塩酸塩 キーワード