メタンフェタミン
化学名:メタンフェタミン
CAS番号.537-46-2
英語名:D-METHAMPHETAMINE
CBNumberCB5101667
MFC10H15N
MW149.24
MOL File537-46-2.mol
别名
(+)-デオキシエフェドリン
(αS)-N,α-ジメチルベンゼンエタンアミン
ノロジン
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メタンフェタミン物理性質
| 融点 | 143°C (estimate) |
| 沸点 | 230.33°C (estimate) |
| 比重(密度) | 0.9285 (estimate) |
| 屈折率 | 1.5105 (estimate) |
| 闪点 | 9℃ |
| 貯蔵温度 | 2-8°C |
| 酸解離定数(Pka) | 10.38±0.10(Predicted) |
| 主な危険性 | F,T |
| Rフレーズ | 11-23/24/25-39/23/24/25 |
| Sフレーズ | 16-36/37-45 |
| RIDADR | 1851 |
| WGK Germany | 1 |
| 国連危険物分類 | 6.1(b) |
| 容器等級 | III |
| 有毒物質データの | 537-46-2(Hazardous Substances Data) |
| 毒性 | A widely abused drug; a sympathomimetic and central stimulant that has been used clinically as an anorectic agent. The use of methamphetamine and related drugs in treating obesity is, however, now generally discredited. It may cause elevation of blood pressure, palpitation, and tachycardia, as well as various CNS effects, including psychotic effects at higher doses. Chronic use of methamphetamine and related compounds, especially at high doses as often occurs with drug abuse, can cause a condition often indistinguishable from schizophrenia. Abrupt withdrawal may cause fatigue, depression, and sleep changes. Methamphetamine is an indirect-acting adrenergic and dopamine agonist that acts principally to release endogenous catecholamines, thereby increasing their synaptic availability. Many of its actions can be blocked by adrenergic and dopamine antagonists. The i.p. LD50 in mice is 70 mg/kg. |
