4-ブチル-1,2-ジフェニル-3,5-ピラゾリジンジオン/N-[2-(ジエチルアミノ)エチル]-2-(4-クロロフェノキシ)アセトアミド,(1:1)

4-ブチル-1,2-ジフェニル-3,5-ピラゾリジンジオン/N-[2-(ジエチルアミノ)エチル]-2-(4-クロロフェノキシ)アセトアミド,(1:1) 化学特性,用途語,生産方法

• Originator

  Perclusone,Anphar-Rolland,France,1967

• Manufacturing Process

  935 g of phenylbutazone are dissolved, with heating to a lukewarm state, in 2.7 liters of acetone containing 20% water, and the mixture is filtered if necessary. 853.5 g of p-chlorophenoxyacetic acid diethylamino ethylamide are dissolved in 300 cc of acetone containing 20% water, and the solution is poured into the phenylbutazone solution. There is slight heating, and the solution clarifies. The salt crystallizes rapidly. Drying is effected on a Buchner funnel and the mixture is washed in 450 cc of acetone containing 20% of water. The 1,702 g of product obtained is recrystallized in 2,450 cc of acetone containing 20% of water and, after drying in an oven at 37°C, 1,585 g (86%) of product are obtained. The product is in the form of a white crystalline powder having a melting point of from 87° to 89°C in the Maquenne block.

• Therapeutic Function

  Analgesic, Antiinflammator

4-ブチル-1,2-ジフェニル-3,5-ピラゾリジンジオン/N-[2-(ジエチルアミノ)エチル]-2-(4-クロロフェノキシ)アセトアミド,(1:1) 上流と下流の製品情報

4-ブチル-1,2-ジフェニル-3,5-ピラゾリジンジオン/N-[2-(ジエチルアミノ)エチル]-2-(4-クロロフェノキシ)アセトアミド,(1:1) 生産企業

Global(7)Suppliers

17449-96-6, 4-ブチル-1,2-ジフェニル-3,5-ピラゾリジンジオン/N-[2-(ジエチルアミノ)エチル]-2-(4-クロロフェノキシ)アセトアミド,(1:1) キーワード