りん酸トリス(2-クロロエチル)

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H302：飲み込むと有害

  H351：発がんのおそれの疑い

  H360：生殖能または胎児への悪影響のおそれ

• 注意書き

  P201：使用前に取扱説明書を入手すること。

  P308+P313：暴露または暴露の懸念がある場合：医師の診断/手当てを 受けること。

りん酸トリス(2-クロロエチル) 価格

MSDS Information

• Tris(2-chloroethyl) phosphate

りん酸トリス(2-クロロエチル) 化学特性,用途語,生産方法

• 外観

  無色～ほとんど無色透明液体

• 用途

  難燃剤、可塑剤

• 主な用途／役割

  リン酸エステル系難燃剤、ＰＶＣの二次可塑剤にもなる。

• 化学的特性

  Tris(2-chloroethyl) phosphate is a clear, light yellow oily liquid with a faintly buttery odor. It is soluble in organic solvents such as ethanol, acetone, chloroform, and carbon tetrachloride, and only slightly soluble in water. The substance is combustible.

• 使用

  Tris(2-chloroethyl) phosphate was used in dynamic air sampling of airborne organophosphate triesters using a solid-phase microextraction device.

• 定義

  ChEBI: Tris(2-chloroethyl) phosphate is a trialkyl phosphate that is the tris(2-chloroethyl) ester of phosphoric acid. It is a trialkyl phosphate and an organochlorine compound.

• 一般的な説明

  Odorless clear liquid. Neutral pH.

• 反応プロフィール

  Tris(2-chloroethyl) phosphate is incompatible with strong oxidizing agents and strong bases.

• 毒性学

  The toxicological data of tris(2-chloroethyl) phosphate, LD50 values of 390-1410 mg/kg (and more than 2000 mg/kg in one study), have been reported for rats following oral administration. The substance is nonirritating to very mildly irritating to the skin and mucous membranes. It was not sensitizing to the skin in guinea pigs. Subchronic administration of tris(2- chloroethyl) phosphate caused increased liver weight in rats and mice. Additionally, rats showed increased kidney weights and degenerative changes in the hippocampus region of the brain. Results of mutagenicity studies on tris(2- chloroethyl) phosphate are not consistent, but the majority of tests were negative. Results of carcinogenicity studies suggest that tris(2-chloroethyl) phosphate possesses a weak tumorigenic activity, possibly via an epigenetic mechanism. When pregnant rats were treated with tris(2- chloroethyl) phosphate, toxic effects were found in the mother, but no fetotoxic or teratogenic effects were observed. Impairment of reproduction was observed in a two-generation study in mice.

• 安全性プロファイル

  Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. A skin and eye irritant. Combustible when exposed to heat or flame. When heated to decomposition it emits very toxic fumes of POx and Cl-. See also PHOSPHATES, CHLORIDES, and ESTERS.

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