ベンズアミジン塩酸塩N水和物

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P304+P340：吸入した場合：空気の新鮮な場所に移し、呼吸しやすい 姿勢で休息させること。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P405：施錠して保管すること。

ベンズアミジン塩酸塩N水和物 価格

ベンズアミジン塩酸塩N水和物 化学特性,用途語,生産方法

• 化学的特性

  white fine crystalline powder

• 使用

  Benzamidine hydrochloride hydrate is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases. It is a proteolytic inhibitor and apoptosis reagent.

• 主な応用

  Benzamidine hydrochloride hydrate has been used:
  in western blot analysis
  in immunoprecipitation
  in the purification of yeast dynein
  as a protease inhibitor in the preparation of brush-border membrane vesicles
  for the processing of human synovial fluid, blood and eye sleep
  to prevent non-specific degradation of cartilages

• 生物活性

  Peptidase inhibitor.
  Benzamidine HCl is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases.A concentration of approximately 1 mM is used for general protease inhibition. To inhibit proteases from yeast, a range of 0.5 to 4.0 mM is used and it is for the most part interchangeable with pepstatin A.
  In addition to being a strong competitive inhibitor of trypsin, benzamidine HCl has been also shown to be a strong competitive inhibitor of thrombin and plasmin. It was also found to be as effective as aprotinin in the prevention of glucagon degradation in human plasma.

• 純化方法

  Recrystallise it from dilute HCl (crystals contain xH2O) or EtOH/few drops HCl; dry it in a vacuum. It is a proteolytic inhibitor [Jeffcoate & White J Clin Endocrinol Metab 38 155 1974, Beilstein 9 IV 898.]

• 予防処置

  Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is hygroscopic in nature.

ベンズアミジン塩酸塩N水和物 生産企業

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