ナラトリプタン塩酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H319：強い眼刺激

• 注意書き

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

ナラトリプタン塩酸塩 価格

ナラトリプタン塩酸塩 化学特性,用途語,生産方法

• 外観

  白色～ほとんど白色粉末～結晶

• 効能

  抗片頭痛薬, 血管収縮薬, セロトニン受容体作動薬

• 商品名

  アマージ (グラクソ・スミスクライン)

• 説明

  Naramig was launched in Germany, Sweden and the UK for use in migraine. It is chemically available via a number of related synthetic routes all having about three steps starting from 5-bromoindole. It is a new serotonin 5-HT_1B/1D receptor antagonist with modest affinity for 5-HT_1a, and very weak affinity for 5-HT₃ receptors. It has little or no affinity for a wide range of non-serotonin receptors including a- and padrenoceptors, dopamine, neurokinin NK₁, and opiate receptors. It mediates vasoconstriction in cerebral vasculature (extra cerebral intracranial vessels), reduces neurogenic inflammation, and inhibits responses mediated by the trigeminal nerves. It has a 6- and 3-fold greater affinity for 5-HT_1B, and 5-HT_1D, receptors, respectively, than sumatriptan which translates to a 2-3 fold increase in potency. The reoccurance of headache was less compared to sumatriptan, zolmitriptan and rizatriptan. Naramig had no clinical effects on blood pressure or heart rate, had a long duration of action with very good tolerability, and has high oral bioavailability.

• 化学的特性

  Beige Solid

• 使用

  Naratriptan Hydrochloride is a triptan drug and is used for the treatment of migraine headaches

ナラトリプタン塩酸塩 生産企業

Global(163)Suppliers

ナラトリプタン塩酸塩 スペクトルデータ(¹HNMR)

143388-64-1, ナラトリプタン塩酸塩 キーワード