4-(DIMETHYLAMINO)-N-[6-(HYDROXYAMINO)-6-OXOHEXYL]-BENZAMIDE

4-(DIMETHYLAMINO)-N-[6-(HYDROXYAMINO)-6-OXOHEXYL]-BENZAMIDE 価格

4-(DIMETHYLAMINO)-N-[6-(HYDROXYAMINO)-6-OXOHEXYL]-BENZAMIDE 化学特性,用途語,生産方法

• 説明

  CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC₅₀ value of 10 μM. Similar potency is observed with trapoxin A and B, whereas trichostatin A is more potent inhibitor of the enzyme. Trichostatin A also selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA. However, trichostatin A is much more expensive than CAY10398. CAY10398 thus represents a selective and cost-effective compound for the inhibition of HDAC.

• 使用

  A histone deacetylase (HDAC1) inhibitor

4-(DIMETHYLAMINO)-N-[6-(HYDROXYAMINO)-6-OXOHEXYL]-BENZAMIDE 生産企業

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