trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene-d8

trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene-d8 化学特性,用途語,生産方法

• 使用

  Labelled trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene (B205800). Benzo[a]pyrene (B205800), a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (D452280) undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNA-adducts primarily with 2'-deoxyguanosine. A carcinogen.

trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene-d8 生産企業

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