ANTI-CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR 化学構造式

ANTI-CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

化学名:ANTI-CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

CAS番号.

英語名:ANTI-CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

CBNumberCB4198590

MW0

ANTI-CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR物理性質

貯蔵温度	-20°C
外見	緩衝グリセロール水溶液

ANTI-CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR 価格

製品番号	包装	価格	製品説明	購入
Sigma-Aldrich Japan SAB4501942	100μG	￥97700	affinity isolated antibody	購入
Sigma-Aldrich Japan C7491	100μG	￥110000	affinity isolated antibody, buffered aqueous solution	購入

ANTI-CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR 化学特性,用途語,生産方法

使用
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
一般的な説明
CFTR (Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette sub-family C, member 7) is a membrane-associated, N-linked glycoprotein.
Biochem/physiol Actions
CFTR (Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette sub-family C, member 7) is mainly involved in the regulation of Na+ and Cl- transport by acting as a linear, cAMP activated, chloride channel. In addition, it is also associated with different transport signaling pathways. It has been reported that CFTR controls functionality of outwardly rectifying Cl- channels (ORCCs) by facilitating the transport and delivery of potent autacoid agonist and ORCC regulator ATP. It has also been suggested that CFTR can interact with Na+-reabsorptive pathway. CFTR is associated with congenital bilateral absence of the vas deferens (CBAVD) and causes the genital form of cystic fibrosis (CF). The CFTR gene may also responsible for male infertility.

ANTI-CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR 生産企業

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