2,3-ジヒドロ-7-ヒドロキシ-2-(4-ヒドロキシフェニル)-5-メトキシ-8-(3-メチル-2-ブテニル)-4H-1-ベンゾピラン-4-オン

2,3-ジヒドロ-7-ヒドロキシ-2-(4-ヒドロキシフェニル)-5-メトキシ-8-(3-メチル-2-ブテニル)-4H-1-ベンゾピラン-4-オン 価格

2,3-ジヒドロ-7-ヒドロキシ-2-(4-ヒドロキシフェニル)-5-メトキシ-8-(3-メチル-2-ブテニル)-4H-1-ベンゾピラン-4-オン 化学特性,用途語,生産方法

• 説明

  Isoxanthohumol is a natural, prenylated chalcone isolated from the hop plant, H. lupulus (hops). It has diverse biological activities, including antiproliferative, anti-inflammatory, and antiviral properties. In B16 and A375 melanoma cells, isoxanthohumol inhibits proliferation (IC₅₀s = 22.15 and 22.9 μM in an MTT assay), slows cell division, and induces apoptosis. Isoxanthohumol reversibly inhibits K_v1.3 channels with an EC₅₀ value of 7.8 μM in human Jurkat T cells using patch clamp electrophysiology. It has strong deterrent properties against the peach potato aphid. It has also been used as a marker of beer consumption. Isoxanthohumol is metabolized in the liver and intestine to 8-prenylnaringenin , a potent phytoestrogen.

• 使用

  Isoxanthohumol is a prenylated flavone isolated from hop. A chromane-like cyclic prenylflavonoids for neurological disorder therapy. Isoxanthohumol is a prenylated flavonoid phytoestrogen which is an apoptosis inducer in mature adipocytes

2,3-ジヒドロ-7-ヒドロキシ-2-(4-ヒドロキシフェニル)-5-メトキシ-8-(3-メチル-2-ブテニル)-4H-1-ベンゾピラン-4-オン 生産企業

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