2-メチルイソニコチンアルデヒド

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

2-メチルイソニコチンアルデヒド 価格

2-メチルイソニコチンアルデヒド 化学特性,用途語,生産方法

• 使用

  2-Methylisonicotinaldehyde belongs to the pyridine group of compounds and is used in the preparation of benzimidazoles and related analogues as sirtuin modulators and in the synthesis of other organic compounds.

• 合成

  2-Methylisonicotinaldehyde is synthesised using methanol as raw material by chemical reaction. The specific synthesis steps are as follows:
  A solution of N,N-dimethyl-2-(2-methyl-4-pyridyl)ethenamine (6.4 g, 39 mmol) in methanol (25 ml) was added dropwise to a mixture of sodium periodate (25.2 g, 117 mmol) and methanol (25 ml) at room temperature.. The mixture was stirred at the same temperature for 1 hr.. The precipitates were filtered off, and the filtrate was concentrated.. The residue was combined with water and extracted with ethyl acetate.. The organic layer was washed with saturated brine and dried over magnesium sulfate.. The solvent was evaporated to give the titled compound (3.7 g, 78 percent).1H-NMR (CDCl3) δ: 2.68 (3H, s), 7.51 (1H, d, J = 4.9 Hz), 7.56 (1H, s), 8.76 (1H, d, J = 4.9 Hz), 10.05 (1H, s).
  

2-メチルイソニコチンアルデヒド 生産企業

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