N-(トリメチルシリル)ジエチルアミン

化学名:N-(トリメチルシリル)ジエチルアミン

CAS番号.996-50-9

英語名:N,N-Diethyl-1,1,1-trimethylsilylamine

CBNumberCB3771284

MFC7H19NSi

MW145.32

别名

N-(トリメチルシリル)ジエチルアミン

ジエチルアミノトリメチルシラン

トリメチルシリルジエチルアミン

N-(トリメチルシリル)ジエチルアミン物理性質

融点	-10°C
沸点	125-126 °C(lit.)
比重(密度)	0.767 g/mL at 25 °C(lit.)
蒸気密度	>1 (vs air)
屈折率	n20/D 1.411(lit.)
闪点	50 °F
貯蔵温度	Keep in dark place,Inert atmosphere,2-8°C
溶解性	Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate (Slightly)
外見	clear liquid
酸解離定数(Pka)	11.27±0.70(Predicted)
比重	0.763
色	Colorless to Light yellow
水溶解度	分解する
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	7: reacts slowly with moisture/water
BRN	635718
CAS データベース	996-50-9(CAS DataBase Reference)
NISTの化学物質情報	N,N-Diethyl-1,1,1-trimethylsilylamine(996-50-9)
EPAの化学物質情報	Silanamine, N,N-diethyl-1,1,1-trimethyl- (996-50-9)

安全性情報

危険有害性情報のコード(GHS)

外観
無色～わずかにうすい黄色, 澄明の液体
溶解性
アセトンに溶けやすく、水及びエタノールによって分解する。
用途
GC分析における前処理剤、シリル化剤。
化学的特性
Colorless liquid
使用
Trimethylsilyldiethylamine is a reagent used as an electrophilic trimethylsilyl source for cleavage of cyclic ethers, esters, oxazolidines, and cyclic acetals; also as a nucleophilic source of the diethylamino group, participating in the following synthesis reactions: Trimethylsilyl Group Transfer, Diethylamino Group Transfer, Trimethylsilyldiethylamine as Halosilane Equivalent, Silylation of Alcohols, Mild Generation of Phosphonochloridates, Silylation of Amines, Diethylamino Group Transfer, Conjugate Addition, Aminoalkylation of Aldehydes, Enamine and Silyl Enol Ether Preparation, Mediation of 1,4-Conjugate Additions, etc.
定義
ChEBI: An N-silyl compound that is diethylamine in which the amino hydrogen is replaced by a trimethylsilyl group. N-(trimethylsilyl)diethylamine is a derivatisation agent used in gas chromatography/mass spectrometry applicat ons.
一般的な説明
N,N-Diethyltrimethylsilylamine is a silylating agent used to derivatize polar organic compounds.
純化方法
Fractionate it through a 2ft vacuum-jacketed column containing Helipak packing with a reflux ratio of 10:1. [Sauer & Hasek J Am Chem Soc 68 241 1946, Langer et al. J Org Chem 23 50 1958, Rühlmann J Prakt Chem 9 315 1959, Beilstein 4 IV 4010.]