メチルドーパート塩酸塩

メチルドーパート塩酸塩 価格

メチルドーパート塩酸塩 化学特性,用途語,生産方法

• 効能

  血圧降下薬

• 使用

  Ethyl methyldopate hydrochloride is Antihypertensive.

• 一般的な説明

  Methyldopatehydrochloride, L-3-(3,4-dihydroxyphenyl)-2-methylalanineethyl ester hydrochloride (Aldomet ester hydrochloride), α-methyldopa, lowers blood pressure by inhibitingthe outflow of sympathetic vasoconstrictor impulses fromthe brain. Early studies had suggested that the hypotensiveaction of α-methyldopa was a result of the peripheral propertiesof the drug as a decarboxylase inhibitor or a falsetransmitter.

• 臨床応用

  Ethyl methyldopate hydrochloride is used as a step 2 agent and is recommendedfor patients with high blood pressure who are not responsiveto diuretic therapy alone. Ethyl methyldopate hydrochloride, suitable for oral use,is a zwitterion and is not soluble enough for parenteral use.The problem was solved by making the ester, leaving theamine free to form the water-soluble hydrochloride salt. It issupplied as a stable, buffered solution, protected with antioxidantsand chelating agents.

メチルドーパート塩酸塩 生産企業

Global(36)Suppliers

2508-79-4, メチルドーパート塩酸塩 キーワード