Silane, trimethyl(2-methylene-3-buten-1-yl)-

Silane, trimethyl(2-methylene-3-buten-1-yl)- 化学特性,用途語,生産方法

• 物理的性質

  bp 69–70 °C/80 mmHg.

• 使用

  2-Trimethylsilylmethyl-1,3-butadiene is an isoprenylation reagent; Diels–Alder diene; reactant in Formation of π-Allylic Complex Followed by Acyldemetalation.

• 製造方法

  2-Trimethylsilylmethyl-1,3-butadiene is prepared most conveniently by the coupling reaction of the Grignard reagent prepared from (chloromethyl)trimethylsilane with 2-chloro-1,3-butadiene (chloroprene) in the presence of a catalytic amount of Ni[Ph2P- (CH2)3PPh2]Cl2 (91% yield) (eq 1). Alternatively, it can be prepared by the reaction of the same Grignard reagent with allenylmethyl phosphate in 57¨C73% yield (eq 2). Direct metalation of isoprene followed by the reaction with chlorotrimethylsilane gives 2-trimethylsilylmethyl-1,3-butadiene in low yield. Thermal isomerization of 1-trimethylsilylmethylcyclobutene to 2-trimethylsilylmethyl-1,3-butadiene has also been reported.

  

Silane, trimethyl(2-methylene-3-buten-1-yl)- 上流と下流の製品情報