IGM 化学特性,用途語,生産方法
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臨床応用
IgM (Fc = μ) is present at a concentration ofabout 1.5 mg/mL and has a half-life of less than 1 week. ThisAb participates in opsonization, agglutination reactions, andcomplement fixation. Opsonization, as stated previously, is a“protein coating” or tagging of a bacterium that renders itmore susceptible to phagocytosis. A complex of the Fc portionof IgM plus C3b of complement is that protein. IgM isthe first immunoglobulin formed during immunization, but itwanes and gives way to IgG. IgM is a pentamer, and its agglutinationpotency is about 1,000 times that of IgG. IgM isalso responsible for the A, B, and O blood groups. The fundamentalmonomeric IgM structure is much like that of IgG.The pentamer is held together by disulfide bonds and a singleJ (joining) peptide. The affinity of an IgM monomer forantigen is less than that of IgG, but the multimeric structureraises the avidity of the molecule for an antigen.
IGM 生産企業
Global(28)Suppliers
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電話番号 021-61415566<br/>800-8193336
電子メール orderCN@merckgroup.com
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Shanghai Yaji Biological Technology Co., Ltd.
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電話番号 02-400-810-9781<br/>400810978
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Shanghai Yubo Biotechnology Co., Ltd
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Hangzhou Xinhe Biotechnology Co., Ltd.
電話番号 15068710863
電子メール
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