LY334370塩酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H400：水生生物に強い毒性

• 注意書き

  P273：環境への放出を避けること。

  P391：漏出物を回収すること。

  P501：内容物/容器を．．．に廃棄すること。

LY334370塩酸塩 価格

LY334370塩酸塩 化学特性,用途語,生産方法

• 説明

  LY334370 is an agonist of the serotonin (5-HT) receptor subtype 5-HT_1F (K_d = 0.446 nM). It is selective for 5-HT_1F over other G protein-coupled 5-HT receptor subtypes with K_i values ranging from 16.4 to greater than 3,000 nM in radioligand binding assays. LY334370 inhibits forskolin-induced cAMP accumulation in mouse L-M(TK-) cell membranes expressing the recombinant human 5-HT_1F receptor (EC₅₀ = 1.51 nM). It decreases electrically stimulated extravasation of plasma proteins in the dura mater in a guinea pig trigeminal nerve model of migraine headache.

• 使用

  LY 334370 Hydrochloride is a 5-HT1f receptor agoniist used potentially in the treatment of migranes.

LY334370塩酸塩 生産企業

Global(16)Suppliers

199673-74-0, LY334370塩酸塩 キーワード