(1R)-1-(4-メトキシフェニル)-2-(メチルアミノ)エタノール

(1R)-1-(4-メトキシフェニル)-2-(メチルアミノ)エタノール 化学特性,用途語,生産方法

• 説明

  This alkaloid, isolated from Dolicothele longimamma, differs from the accompanying bases in not having an isoquinoline structure. Instead, it belongs to the phenethylamine class of alkaloids. It is extracted from the EtOH fraction as the crystalline hydrochloride which forms colourless needles with m.p. 144- 6°C. This salt is optically active with a specific rotation of [α]²⁵_D - 76° and gives an ultraviolet spectrum in EtOH having absorption maxima at 225, 274 and 281 nm. The free base, prepared from the hydrochloride by standard chemical methods cannot be obtained in a crystalline form.

• 参考文献

  Ranieri, McLaughlin,J. Org. Chem., 41, 319 (1976)