BICALUTAMIDE-D4

BICALUTAMIDE-D4 化学特性,用途語,生産方法

• 説明

  Bicalutamide-d₄ is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (K_i = 12.5 μM; IC₅₀ = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.

• 化学的特性

  BICALUTAMIDE-D4 is White Solid

• 使用

  BICALUTAMIDE-D4 is used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0

BICALUTAMIDE-D4 生産企業

Global(38)Suppliers

1185035-71-5, BICALUTAMIDE-D4 キーワード