ラミニン EHS肉腫基底膜由来

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

ラミニン EHS肉腫基底膜由来 価格

ラミニン EHS肉腫基底膜由来 化学特性,用途語,生産方法

• 使用

  Laminin from human fibroblasts has been used:
  
  • in coating six-well plates for wound healing assay
  • as a substrate in cell adhesion and spreading assay
  • for differentiation of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) toward dopaminergic neurons
  • in corneal endothelial cell wound healing (migration) assay and corneal endothelial cell barrier assay
  
  Laminin from human fibroblasts is recommended for use as a cell culture substratum at 1-2 μg/cm². The optimal concentration does depend on cell type as well as the application or research objectives.

• 一般的な説明

  Laminin is purified as laminin-nidogen complex from mouse Engelbreth-Holm-Swarm (EHS) sarcoma. Laminin is a heterotrimer made from α, β and γ chain subunits. It is a glycoprotein which is required for the structural scaffolding of basement membranes. Laminin supports growth and differentiation of many cell types including epithelial, endothelial, neural, muscle and liver cells.
  
  Biological activity: Tested for the promotion of adherence of HT-1080 cells.
  Species specificity: Active on most mammalian cells.

• Biochem/physiol Actions

  Laminin proteins are integral components of structural scaffolding in animal tissues. They associate with type IV collagen via entactin and perlecan and bind to cell membranes through integrin receptors, dystroglycan glycoprotein complexes and Lutheran blood group glycoproteins. Laminin has active domains for collagen binding, cell adhesion, heparin binding, and neurite outgrowth fragment.

ラミニン EHS肉腫基底膜由来 生産企業

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