ブジピン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H315：皮膚刺激

  H319：強い眼刺激

  H332：吸入すると有害

  H335：呼吸器への刺激のおそれ

• 注意書き

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P310：ただちに医師に連絡すること。

ブジピン 価格

ブジピン 化学特性,用途語,生産方法

• 効能

  パーキンソン病治療薬

• 説明

  Parkinsan was launched in Germany as a centrally-active anti-Parkinsonian agent. It can be prepared in three steps: a Mannich-aldol sequence to assemble the 4-phenylpiperidine scaffold followed by a Friedel-Crafts reaction to introduce the second phenyl ring. Parkinsan is effective for the treatment of Parkinsonian tremors and is similar in action to, but more potent than, biperiden. It exhibits use-dependent, open channel, uncompetitive NMDA receptor antagonistic activity. This may occur by binding to the PCP site in addition to interacting with sigma, binding sites in the frontal cortex. Parkinsan is also an antagonist at presynaptic muscarinic autoreceptors but facilitation of direct or indirect dopaminergic transmission does not contribute to its actions. While its mechanism of action is not completely understood, it has a weak inhibitory effect on dopamine reuptake, inhibits evoked GABA release (with low affinity for GABA-A receptors and a lower affinity for benzodiazepine receptors), and has a weak inhibitory effect on MAO-B.

ブジピン 上流と下流の製品情報

ブジピン 生産企業

Global(52)Suppliers

ブジピン スペクトルデータ(¹HNMR)

57982-78-2, ブジピン キーワード