5-OXO-6Z,9S-(S-GLUTATHIONYL)-11Z,14Z-EICOSATRIENOIC ACID

5-OXO-6Z,9S-(S-GLUTATHIONYL)-11Z,14Z-EICOSATRIENOIC ACID 化学特性,用途語,生産方法

• 説明

  FOG9 is formed through the conjugation of 5-oxoETE with glutathione in a 1,6 Michael addition at C-9. The biological activity of FOG9 has not been determined. However, FOG7, a 1,4-adduct formed within murine peritoneal macrophages, was found to be highly potent in stimulating eosinophil and neutrophil chemotaxis. FOG7 was also capable of initiating actin polymerization without elevating intracellular free calcium ion concentration within either the eosinophil neutrophils or PMNL.

5-OXO-6Z,9S-(S-GLUTATHIONYL)-11Z,14Z-EICOSATRIENOIC ACID 生産企業

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