ビキニン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H319：強い眼刺激

• 注意書き

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

ビキニン 価格

ビキニン 化学特性,用途語,生産方法

• 外観

  白色～ほとんど白色粉末～結晶

• 使用

  Bikinin has been used:
  
  • as a glycogen synthase kinase-3 (GSK3) inhibitor in Arabidopsis Col-0 seedlings to test its effect on gene expression
  • as a component of induction medium and as a GSK3 inhibitor to test its effect on mesophyll cells in Arabidopsis leaf discs or cotyledons
  • as a brassinosteroid agonist to test its effect on the leaf index of R. trichophyllus terrestrial leaves
  
  

• Biochem/physiol Actions

  Bikinin is a strong activator of brassinosteroid (BR) signaling. It is an Arabidopsis GSK-3 Inhibitor, an Arabidopsis SHAGGY-related Kinase Inhibitor, and a GSK-3-like Kinase BIN2 Inhibitor. Bikinin directly inhibits BIN2 (group II GSK3s) by interfering with ATP binding. Bikinin is specific toward a subset of Arabidopsis GSK3 kinases including BIN2 and ASK α, γ, ε, ι, and θ.

• 酵素阻害剤

  This ATP-competitive Arabidopsis GSK-3 inhibitor, (FW = 273.08 g/mol; CAS 188011-69-0), also named 4-(5-bromopyridin-2-ylamino)-4- oxobutanoic acid, is a strong activator of brassinosteroid (BR) signaling. Bikinin directly binds the GSK3 BIN2 and also inhibits the activity of six other Arabidopsis GSK3s. Genome-wide transcript analyses demonstrate that simultaneous inhibition of seven GSK3s is sufficient to activate BR responses. inhibited the SnRK2.3 kinase activity and its T180 phosphorylation in vivo by blocking BIN2 phosphorylation of SnRK2.3 on Thr-180.

ビキニン 生産企業

Global(121)Suppliers

ビキニン スペクトルデータ(¹HNMR)

188011-69-0, ビキニン キーワード