抗LC3抗体 ウサギ宿主抗体

抗LC3抗体 ウサギ宿主抗体 化学特性,用途語,生産方法

• 使用

  Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
  Immunofluorescence (3 papers)
  Immunohistochemistry (1 paper)
  Western Blotting (21 paper)

• 一般的な説明

  The gene LC3, also referred to as MAP1LC3A (microtubule associated protein 1 light chain 3 α), is a homologue of Apg8p necessary for autophagy in yeast. The cytosolic form upon processing gets localized to the autophagosome membranes. The gene is mapped to human chromosome 20q11.22. LC3 exists in cells as cytoplasmic LC3-I (18kDa) and LC3-II (16kDa).

• Biochem/physiol Actions

  The gene MAP1LC3A (microtubule associated protein 1 light chain 3 α) encodes a protein that serves as a marker of autophagosomes. It is found to be expressed on surviving oligodendrocytes in Nasu-Hakola disease brains and may be involved in the induction of oligodendrogliopathy.

抗LC3抗体 ウサギ宿主抗体 生産企業

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