MeningococcalPolysaccharideVaccine

MeningococcalPolysaccharideVaccine 化学特性,用途語,生産方法

• 一般的な説明

  Meningococcal vaccine is an inactivated vaccine composedof capsular polysaccharide fragments of Neisseria meningitidis.There are four polysaccharide serotypes represented inthe vaccine: A, C, Y, and W-135. The type A polysaccharideconsists of a polymer of N-acetyl-O-mannosamine phosphate;the group C polysaccharide is mostly N-acetyl-Oacetylneuraminicacid. The antigens are conjugated to diphtheriatoxoid carrier. Indications are the following:
  ? Induction of active immunity against selected strains ofN. meningitidis
  ? Military recruits during basic training
  ? College freshmen and those living in dormitories
  ? Travelers to countries with epidemic meningococcal disease? Household or institutional contacts of those with meningococcaldisease
  ? Immunosuppressed persons (HIV, Streptococcus pneumoniae)
  ? To stop certain meningococcal group C outbreaks
  ? Persons aged 2 through 55 years of age at risk for invasivemeningococcal disease.