1,2-ヘキサンジオール

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H319：強い眼刺激

• 注意書き

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

1,2-ヘキサンジオール 価格

MSDS Information

• DL-1,2-Hexanediol

1,2-ヘキサンジオール 化学特性,用途語,生産方法

• 外観

  無色～ほとんど無色, 澄明の液体

• 定義

  本品は、次の化学式で表される二価アルコールである。

• 溶解性

  水、エタノール及びアセトンに極めて溶けやすい。

• 用途

  有機合成用試薬。

• 化粧品の成分用途

  防腐剤、溶剤

• 説明

  1,2-Hexanediol is a linear aliphatic diol with a carbon chain length containing six carbons. It is a synthetic preservative and moisture-binding agent belonging to a class of agents known as higher molecular glycols. It is considered non-sensitizing. It is ideal for use as an emollient, humectant, and wetting agent in cosmetic and skin care products.

• 化学的特性

  clear colorless to light yellow liquid.

• 製造方法

  1,2-Hexanediol was synthesized with an overall yield of approximately 45% using a multi-step process that involved a-bromination of caproic acid, followed by hydrolysis to a-hydroxycaproic acid, and concluded with reduction using lithium aluminum hydride. In an alternate method, the organic acid was oxidized with H2O2 to form a peroxy acid, which in turn epoxidized the olefin double bond and ultimately underwent hydrolysis to yield 1,2-hexanediol.
  SYNTHESIS OF SOME HEXANEDIOLS

• 主な応用

  In skin care: 1,2-Hexanediol  is one of the most multi-functional ingredients in the cosmetic  industry. It is used in skin care, hair care as well as beauty products.  It is a great emollient as well as a humectant, that is, it preserves hydration on the skin while also softening it.

• 利点

  1,2 hexanediol is most commonly used as a solvent in skincare formulation. It pulls the moisture up from the deeper levels of the skin, as well as from the air, to help keep the top layers of your skin from drying out. This makes It very effective at keeping your skin hydrated and providing long-term moisture. It can also help to disperse pigments more evenly in makeup products and boost the antimicrobial activity of preservatives.

• 一般的な説明

  1,2-Hexanediol acts as cosurfactant, used for modifying the sodium dodecyl sulfate micelles. Solubility of 1,2-hexanediol in supercritical CO₂ has been reported. It has a tendency of self-association to form micelle-like aggregates.

• 安全性

  1,2-Hexanediol is safe for skin and hair when used in lower concentrations. In an in-use safety evaluation for skin irritation and sensitization potential, 28 participants (males and females) were instructed to use a body wash containing 0.15% 1,2- hexanediol for a minimum of 3 times per week over a 30-day period. There was no evidence of erythema, edema, or dryness of application sites in any of the participants, and it was concluded that the product did not demonstrate a potential for eliciting skin irritation or sensitization.
  Safety Assessment of 1,2-Glycols as Used in Cosmetics

• 純化方法

  Fractionally distil it, preferably in a vacuum. Alternatively, dissolve it in Et2O, dry with K2CO3 then Na2SO4, filter, evaporate and distil it in a vacuum. The bis-4-nitrobenzoyl derivative has m 101.5-102.5o. [Rudloff Can J Chem 36 486 1958, Beilstein 1 I 251, 1 III 2200, 1 IV 2554.]

1,2-ヘキサンジオール 上流と下流の製品情報

1,2-ヘキサンジオール 生産企業

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1,2-ヘキサンジオール スペクトルデータ(¹HNMR、¹³CNMR、IR1、MS、Raman)

6920-22-5, 1,2-ヘキサンジオール キーワード