2α-メチル-17β-ヒドロキシ-5α-アンドロスタン-3-オン

2α-メチル-17β-ヒドロキシ-5α-アンドロスタン-3-オン 化学特性,用途語,生産方法

• 説明

  Drostanolone, also known as Dromostanolone[58-19-5], is an anabolic hormone and a derivative of methyltestosterone. Its action is similar to that of Conviron. Its anabolic effect is 4 times that of methyltestosterone and its androgenic activity is 0.39 times that of the latter. It is clinically used in the treatment of chronic wasting disease, pediatric underdevelopment, old age and frailty, serious illness and postoperative weakness, osteoporosis, aplastic anemia, leukopenia, thrombocytopenia, and hyperlipidemia.

• 化学的特性

  White or off-white crystalline powder, odorless. Insoluble in water, slightly soluble in ethanol, slightly soluble in ether, soluble in chloroform.

• 使用

  Drostanolone is a synthetic estrogen antagonist and is classified as an anabolic androgenic steroid. It has been used in sports to improve athletic performance and can be detected in urine. In the United States, Drostanolone is classified as a Schedule III substance, indicating it is regulated and controlled. This product is intended for research and forensic applications.

• Mode of action

  It can promote protein synthesis and inhibit protein xenobiosis, reduce calcium and phosphorus excretion and alleviate bone marrow suppression, promote growth and development, promote tissue renewal and granulation, and reduce blood cholesterol, and have preventive and antagonistic effects on adrenocorticotropic hormone long-term use of adrenocorticotropic hypoplasia and protein anisotropy.

• 参考文献

  [1] SCH?NZER W, DONIKE M. Metabolism of anabolic steroids in man: synthesis and use of reference substances for identification of anabolic steroid metabolites[J]. Analytica Chimica Acta, 1993, 275: 23-48. DOI:10.1016/0003-2670(93)80274-O.
  [2] KINTZ P, GHEDDAR L. Evidence of use of drostanolone, an anabolic steroid, at the time the subject committed a murder: Place of hair analysis[J]. Toxicologie Analytique et Clinique, 2021. DOI:10.1016/J.TOXAC.2021.05.002.
  [3] LIU Y, LU J, YANG S, et al. New drostanolone metabolites in human urine by liquid chromatography time-of-flight tandem mass spectrometry and their application for doping control[J]. Steroids, 2016, 108: 61-67. DOI:10.1016/j.steroids.2016.01.013.

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58-19-5, 2α-メチル-17β-ヒドロキシ-5α-アンドロスタン-3-オン キーワード