ChemicalBook >  製品カタログ >  食品添加物 >  防腐剤 >  ソルビン酸

ソルビン酸

ソルビン酸 化学構造式
110-44-1
  • CAS番号.110-44-1
  • 化学名:ソルビン酸
  • 别名:ソルビン酸;(E,E)-ソルビン酸;2-プロペニルアクリル酸;2,4-ヘキサジエン酸;(2E,4E)-2,4-ヘキサジエン酸;ソルビン酸標準品;ソルビン酸 [生化学用];(2E,4E)-ヘキサ-2,4-ジエン酸
  • 英語化学名:Sorbic acid
  • 英語别名:sorbic;hexa-2,;Panosorb;Sorbistat;FEMA 3921;C6:2n-2,4;NSC 35405;NSC 49103;NSC 50268;Sorbinsure
  • CBNumber:CB1748891
  • Molecular Formula:C6H8O2
  • Formula Weight:112.13
  • MOL File:110-44-1.mol
ソルビン酸 物理性質
  • 融点  :132-135 °C(lit.)
  • 沸点  :228°C
  • 比重(密度)  :1,205 g/cm3
  • 蒸気圧 :0.01 mm Hg ( 20 °C)
  • FEMA  :3921 | 2,4-HEXADIENOIC ACID, (E,E)-
  • 屈折率  :1.4600 (estimate)
  • 闪点  :127 °C
  • 貯蔵温度  :2-8°C
  • 溶解性 :ethanol: 0.1 g/mL, clear
  • 酸解離定数(Pka) :4.76(at 25℃)
  • 外見  :Crystalline Powder
  • 色 :White or cream-white
  • PH :3.3 (1.6g/l, H2O, 20°C)
  • 水溶解度  :1.6 g/L (20 ºC)
  • JECFA Number :1176
  • Merck  :14,8721
  • BRN  :1741831
  • 安定性: :Stability Material saturated with this acid may ignite spontaneously. Incompatible with strong oxidizing agents. May be light sensitive.
  • InChIKey :WSWCOQWTEOXDQX-MQQKCMAXSA-N
  • CAS データベース :110-44-1(CAS DataBase Reference)
  • NISTの化学物質情報 :2,4-Hexadienoic acid, (E,E)-(110-44-1)
  • EPAの化学物質情報 :Sorbic acid (110-44-1)
安全性情報
  • 主な危険性  :Xi
  • Rフレーズ  :36/37/38-36/38
  • Sフレーズ  :26-36-24/25
  • WGK Germany  :1
  • RTECS 番号 :WG2100000
  • F  :8
  • 自然発火温度 :>130 °C
  • TSCA  :Yes
  • HSコード  :29161930
  • 有毒物質データの :110-44-1(Hazardous Substances Data)
  • 毒性 :LD50 orally in rats: 7.36 g/kg (Smyth, Carpenter)
危険有害性情報のコード(GHS)
  • 絵表示(GHS)
  • 注意喚起語Warning
  • 危険有害性情報
  • H315:皮膚刺激
  • H319:強い眼刺激
  • H335:呼吸器への刺激のおそれ
  • 注意書き
  • P261:粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
  • P280:保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
  • P304+P340:吸入した場合:空気の新鮮な場所に移し、呼吸しやすい 姿勢で休息させること。
  • P305+P351+P338:眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。
  • P337+P313:眼の刺激が続く場合:医師の診断/手当てを受けること。
  • P405:施錠して保管すること。

ソルビン酸 MSDS


Sorbic acid

Sorbic acid 化学特性,用途語,生産方法

  • 外観 白色〜ほとんど白色, 結晶〜結晶性粉末
  • 定義 本品は、次の化学式で表される有機酸である。
  • 溶解性 エタノール及びジエチルエーテルに溶け、水にほとんど溶けない。水に微溶 (30℃で0.25%)。エタノールに12.5%, メタノールに20%可溶。
  • 用途 中性または酸性で抗カビ力がすぐれ、特定食品の抗カビ剤に用いられる。また合成樹脂の原料にもなる。
  • 用途 防腐剤、保存料
  • 化粧品の成分用途 防腐剤、香料
  • 効能 抗菌性保存剤
  • 使用上の注意 重合しやすい。
  • 化学的特性 White, crystalline solid. Slightly soluble in water and many organic solvents. Combustible.
  • 化学的特性 (E,E)-2,4-Hexadienoic acid has a characteristic odor.
  • 使用 Sorbic Acid is a preservative that is effective against yeasts and molds. it is effective over a broad ph range up to ph 6.5, being ineffective above ph 7.0. it is a white, free-flowing powder which is slightly soluble in water with a solubility of 0.16 g in 100 ml of water at 20°c. its solubility in water increases with increasing temperatures, although it is not recommended in foods that are pasteurized because it breaks down at high temperatures. the salts are potas- sium, calcium, and sodium sorbate. it is used in cheese, jelly, bever- ages, syrup, and pickles. typical usage levels range from 0.05 to 0.10%.
  • 使用 Sorbic Acid is an naturally occurring organic compound first isolated from unripe berries. Sorbic acid has been used as a food preservative and as an inhibitor of Clostridium Botulinum bacteria in mea t products in order to reduce the amount of nitrites which produce carcinogenic nitroamines.
  • 使用 Mold and yeast inhibitor. Fungistatic agent for foods, especially cheeses. To improve the characteristics of drying oils. In alkyd type coatings to improve gloss. To improve milling characteristics of cold rubber. See also Potassium Sorbate.
  • 使用 sorbic acid is a broad-spectrum, non-toxic preservative against molds and yeasts with moderate sensitizing potential in leave-on cosmetics. It is used in concentrations of 0.1 to 0.3 percent, and its activity is dependent on the formulation’s pH. Sorbic acid is used as a replacement for glycerin in emulsions, ointments, and various cosmetic creams. It is obtained from the berries of the tree commonly known as mountain ash and rowan, and can also be produced synthetically. Sorbic acid can cause irritation.
  • 定義 ChEBI: A sorbic acid having trans-double bonds at positions 2 and 4; a food preservative that can induce cutaneous vasodilation and stinging upon topical application to humans. It is the most thermodynamically stable of the four possible geometri isomers possible, as well as the one with the highest antimicrobial activity.
  • Biotechnological Production Today, sorbic acid is produced solely by chemical synthesis. However, fermentation and chemical synthesis might be combined to develop a new production route for sorbic acid . In a first step, glucose would be converted to triacetic acid lactone by fermentation. It has been shown that triacetic acid lactone can be produced by genetically modified E. coli and S. cerevisiae strains. After a separation from the fermentation broth, triacetic acid lactone would be transformed into butyl sorbate in a multistage catalyst system (catalysis-hydrogenation and solid acid catalysis). Then, butyl sorbate would be purified and hydrolyzed to sorbic acid. Different scenarios are analyzed to evaluate the economic feasibility of such a production process .
  • 一般的な説明 White powder or crystals. Melting point 134.5°C. Slightly acidic and astringent taste with a faint odor.
  • 空気と水の反応 Soluble in hot water [Handbook of Chemistry and Physics]. May be sensitive to exposure to air and heat. The dust may become explosive, particularly when mixed with free-radical initiators or oxidizing agents. .
  • 反応プロフィール Sorbic acid may discolor on exposure to light. Can react with oxidizing agents. Also incompatible with bases and reducing agents. The dust may become explosive, particularly when mixed with free-radical initiators or oxidizing agents .
  • 火災危険 Sorbic acid is combustible.
  • 安全性プロファイル Moderately toxic by intraperitoneal and subcutaneous routes. Mildly toxic by ingestion. Experimental reproductive effects. A severe human and experimental skin irritant. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use water. When heated to decomposition it emits acrid smoke and irritating fumes.
  • 毒性学 Sorbic acid and its salts have broad-spectrum activity against yeast and molds, but are less active against bacteria. The antimicrobial action of sorbic acid was discovered independently in the United States and Germany in 1939, and since the mid-1950s sorbates have been increasingly used as preservatives. Sorbates generally have been found superior to benzoate for preservation of margarine, fish, cheese, bread, and cake. Sorbic acid and its potassium salts are used in low concentrations to control mold and yeast growth in cheese products, some fish and meat products, fresh fruits, vegetables, fruit beverages, baked foods, pickles, and wines. Sorbic acid is practically nontoxic. Table 10.4 shows acute toxicity of sorbic acid and its potassium salt. Animal studies have not shown obvious problems in tests performed with large doses for longer time periods. When sorbic acid (40 mg/kg/day) was injected directly into the stomach of male and female mice for 20 months, no differences were observed in survival rates, growth rates, or appetite between the injected mice and the control. When the dose was increased to 80 mg/kg/day for three additional months, however, some growth inhibition was observed. When potassium sorbate (1 and 2% in feed) was fed to dogs for three months, no pathological abnormalities were observed. This evidence indicates that the subacute toxicity of sorbic acid is negligible.
    As a relatively new food additive, sorbate has been subject to stringent toxicity-testing requirements. It may well be the most intensively studied of all chemical food preservatives. In 90-day feeding studies in rats and dogs and a lifetime feeding study in rats, a 5% dietary level of sorbates procured no observable adverse effects. However, at a 10% dietary level in a 120- day feeding study, rats showed increased growth and increased liver weight. This has been attributed to the caloric value of sorbate at these high dietary levels since it can act as a substrate for normal catabolic metabolism in mammals. Sorbates are not mutagenic or tumorigenic, and as noted previously, no reproductive toxicity has been observed.
  • Carcinogenicity Wistar rats (six males) given subcutaneous injections of 2mg sorbic acid, in 0.5mL of arachis oil twice weekly for 65 weeks developed local sarcomas . The first tumor was observed at 82 weeks. Similar findings were also observed in follow-up studies . However, six Wistar rats maintained on drinking water containing 10 mg of sorbic acid/100mL drinking water for 64 weeks did not develop tumors. Tumors also were not observed inWistar rats (50 of each sex) on diets that contained 40 mg/kg/day of sorbic acid for 18 months or in 25 male and female cross-bred white mice after administration of 40 mg/kg/day for 17 months.
    Mice fed a diet containing 15% sorbic acid for 88 weeks exhibited a high incidence of hepatoma. Furthermore, the glutathione level in the livers of the mice that ingested 15% sorbic acid decreased to 40% of the amount found in controls after a 3-month feeding period; this low level was maintained until the end of the experiments at 12 months. There was a close correlation between the extent of depletion of the glutathione level in the liver and the concentration of sorbic acid added to the diet. In the same strain of mice fed a diet containing 15% sorbic acid for up to 6 months, the acidic fraction of an ether extract showed slight mutagenic activity in an Ames test with Salmonella typhimurium TA98 in the presence of a liver 9000-g supernatant. Consequently, the hepatomas that developed in mice fed a 15% sorbic acid diet were considered to be induced both by the chronic depletion of the hepatic glutathione and by the gradual production of various promutagens in the intestine, which were absorbed and metabolically activated by the liver.
  • 純化方法 Crystallise the acid from water. Dry it air or in a desiccator over P2O5. [Beilstein 2 IV 1701.]
ソルビン酸 上流と下流の製品情報
原材料
準備製品
ソルビン酸 生産企業
Global(420)Suppliers
  • 名前:Henan DaKen Chemical CO.,LTD.
  • 電話番号:+86-371-55531817
  • ファックス番号:
  • 電子メール:info@dakenchem.com
  • 国籍:CHINA
  • 製品カタログ:21806
  • 優位度:58
  • 名前:Henan Tianfu Chemical Co.,Ltd.
  • 電話番号:0371-55170693
  • ファックス番号:0371-55170693
  • 電子メール:info@tianfuchem.com
  • 国籍:CHINA
  • 製品カタログ:22631
  • 優位度:55
  • 名前:Hefei TNJ Chemical Industry Co.,Ltd.
  • 電話番号:86-0551-65418684 18949823763
  • ファックス番号:86-0551-65418684
  • 電子メール:info@tnjchem.com
  • 国籍:China
  • 製品カタログ:2368
  • 優位度:55
  • 名前:Shanghai Zheyan Biotech Co., Ltd.
  • 電話番号:18017610038
  • ファックス番号:
  • 電子メール:zheyansh@163.com
  • 国籍:CHINA
  • 製品カタログ:3623
  • 優位度:58
  • 名前:career henan chemical co
  • 電話番号:+86-371-86658258
  • ファックス番号:
  • 電子メール:sales@coreychem.com
  • 国籍:CHINA
  • 製品カタログ:30052
  • 優位度:58
  • 名前:Chemwill Asia Co.,Ltd.
  • 電話番号:86-21-51086038
  • ファックス番号:86-21-51861608
  • 電子メール:chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com
  • 国籍:CHINA
  • 製品カタログ:23979
  • 優位度:58
  • 名前:Hubei Jusheng Technology Co.,Ltd.
  • 電話番号:86-18871470254
  • ファックス番号:027-59599243
  • 電子メール:linda@hubeijusheng.com
  • 国籍:CHINA
  • 製品カタログ:28235
  • 優位度:58
  • 名前:Haihang Industry Co.,Ltd
  • 電話番号:86-531-88032799
  • ファックス番号:+86 531 8582 1093
  • 電子メール:export@haihangchem.com
  • 国籍:CHINA
  • 製品カタログ:14164
  • 優位度:58
  • 名前:hdzhl biotechnology co., ltd
  • 電話番号:86-13032617415
  • ファックス番号:
  • 電子メール:sales@luchibiology.com
  • 国籍:CHINA
  • 製品カタログ:1278
  • 優位度:58
  • 名前:Chongqing Chemdad Co.,Ltd
  • 電話番号:+86-19923101450
  • ファックス番号:
  • 電子メール:sales@chemdad.com
  • 国籍:CHINA
  • 製品カタログ:4001
  • 優位度:58
110-44-1, ソルビン酸 キーワード:
  • 110-44-1
  • Sorbic acid solution
  • SORBIC ACID(RG)
  • Sorbic acid, 99.8%
  • Sorbic acid 0
  • Sorbic Acid, Natural
  • Sorbic acid tested according to Ph.Eur.
  • Sorbic acid Vetec(TM) reagent grade, 98%
  • (2-butenylidene)-aceticaci
  • (2E,4E)-2,4-Hexadienoic acid
  • Penta-1,3-diene-1-carbo-xylicacid
  • Preservastat
  • sorbic
  • Sorbic acid, (E,E)-
  • Sorbistat
  • Sorbic acid, CP,99%
  • trans,trans-Sorbic acid
  • trans,trans-sorbicacid
  • 1-Bromo-3.5-dichlorobenzene sorbic acid
  • Sorbic acid(SA)
  • SORBIC ACID, PH EUR
  • SORBIC ACID FREE ACID INSECT CELL*CULTUR E TESTED
  • 2,4-HEXADIENOIC ACID, 99+%
  • SORBIC ACID, 1GM, NEAT
  • SORBIC ACID FREE ACID
  • SorbicAcid(FoodGrade)
  • SorbicAcidPuriss
  • SorbicAcidC6H8O2
  • SorbicAcid>99%
  • SORBIC ACID PURE
  • 2,4-Hexadienoic acid, (2E,4E)-
  • ソルビン酸
  • (E,E)-ソルビン酸
  • 2-プロペニルアクリル酸
  • 2,4-ヘキサジエン酸
  • (2E,4E)-2,4-ヘキサジエン酸
  • ソルビン酸標準品
  • ソルビン酸 [生化学用]
  • (2E,4E)-ヘキサ-2,4-ジエン酸
  • 保存料