ジクロフェナック‐D4(フェニル‐D4)

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

ジクロフェナック‐D4(フェニル‐D4) 価格

ジクロフェナック‐D4(フェニル‐D4) 化学特性,用途語,生産方法

• 説明

  Diclofenac-d₄ is intended for use as an internal standard for the quantification of diclofenac (Item Nos. 70680 | 22983) by GC- or LC-MS. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC₅₀s = 0.9-2.7 and 1.5-20 μM, for human COX-1 and COX-2, respectively). It is also an active metabolite of diclofenac methyl ester and diclofenac amide . Diclofenac inhibits release of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) induced by A23187 in isolated rat peritoneal neutrophils and macrophages (IC₅₀s = 60 and 10 μM, respectively). Transdermal administration of diclofenac inhibits carrageenan-induced paw edema in rats. Formulations containing diclofenac have been used in the treatment of pain associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

• 化学的特性

  Off-White Crystalline Solid

• 使用

  Labeled Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. 92% overall isotopic purity. A representative lot was 75% d4, 23% d3 and 2 % d2

ジクロフェナック‐D4(フェニル‐D4) 生産企業

Global(55)Suppliers

153466-65-0, ジクロフェナック‐D4(フェニル‐D4) キーワード