グルカゴン様ペプチド 1 (7-37)

グルカゴン様ペプチド 1 (7-37) 価格

グルカゴン様ペプチド 1 (7-37) 化学特性,用途語,生産方法

• 説明

  GLP-1 (7-37) is an endogenous truncated form of GLP-1 that arises from proglucagon processing in intestinal endocrine L cells, GLP-1 (7-37) acts as a GLP-1 receptor agonist and is an insulinotropic hormone that augments glucose induced insulin secretion. GLP-1 (7-37) and derivatives GLP-1 (9-37) and GLP-1 (28-37) can reduce plaque inflammation and increase phenotypic characteristics of plaque stability in a murine model of atherosclerosis.

• 使用

  Glucagon-Like Peptide 1 Fragment 7-37 human has been used:
  
  • as a positive control for insulin secretion of pancreatic islets
  • to test its effect on insulin response in horse islets
  • in combination with mesenchymal stem cells (MSCs) test its protective effects in myocardial infarction
  
  

• 一般的な説明

  Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) is an amino-truncated form of GLP-1.

• Biochem/physiol Actions

  Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) interacts with the GLP-1 receptor (GLP-1r). It mediates insulin release by stimulating the cyclic AMP accumulation in islet cells GLP-l(7-37) is a potential therapeutic agent due to its insulin-secretagogue functionality.

グルカゴン様ペプチド 1 (7-37) 生産企業

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