プロパフェノン·塩酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

プロパフェノン·塩酸塩 価格

プロパフェノン·塩酸塩 化学特性,用途語,生産方法

• 外観

  白色～ほとんど白色粉末～結晶

• 溶解性

  メタノール、ギ酸に可溶

• 用途

  ナトリウムチャネルを遮断し、 活動電位の立ち上がりを抑制します。

• 用途

  ナトリウムチャネルを遮断し、 活動電位の立ち上がりを抑制します。

• 効能

  抗不整脈薬, ナトリウムチャネル遮断薬

• 商品名

  プロノン (トーアエイヨー)

• 説明

  Propafenone hydrochloride is a class I anti-arrhythmic agent with basic local anaesthetic and membrane-stabilizing properties. Some P-adrenergic blocking action has also been described. Propafenone decreases the depolarization velocity and slows conduction in the His-Purkinje system with resultant increase in the PR interval and the QRS complex. Propafenone is used in the treatment of paroxysmal supraventricular tachycardias and ventricular arrhythmias.
  Propafenone should not be used in uncontrolled cardiac failure, severe obstructive pulmonary disease or marked hypotension. Propafenone may worsen myasthenia gravis.

• 化学的特性

  White Solid

• 使用

  Propafenone hydrochloride is a class IC antiarrhythmic agent used for the management of severe ventricular and supraventricular arrhythmias. It has beta-blocking and weak calcium channel blocking properties, as well as some negative inotropic activity. Propafenone is in a class of medications called antiarrhythmics. It works by acting on the heart muscle to improve the heart's rhythm.

• 使用

  Sodium channel blocker. Antiarrhythmic (class IC)

• 定義

  ChEBI: Propafenone hydrochloride is a hydrochloride that is the monohydrochloride salt of propafenone. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used in the management of supraventricular and ventricular arrhythmias. It has a role as an anti-arrhythmia drug. It contains a propafenone(1+).

• 薬物動態学

  Propafenone hydrochloride (Rythmol(R)) is similar in action to flecainide. It reduces the fast inward sodium current in Purkinje fibres and to a lesser extent in myocardial fibres. Unlike other class l drugs, propafenone has mild B-blocking effects. This may contribute to its overall effects on the conduction system. lt is also believed to have calcium channel-blocking effects, which may contribute to its mild negative inotropic effects.

プロパフェノン·塩酸塩 上流と下流の製品情報

プロパフェノン·塩酸塩 生産企業

Global(358)Suppliers

プロパフェノン·塩酸塩 スペクトルデータ(¹HNMR)

34183-22-7, プロパフェノン·塩酸塩 キーワード