1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt)

1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt) 価格

1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt) 化学特性,用途語,生産方法

• 使用

  Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.

• 一般的な説明

  Lysophosphatidic?acid (LPA) is a class of phospholipids, which is water-soluble. It has a glycerol backbone attached?via?a phosphate group, an aliphatic chain and a hydroxyl group.?The aliphatic chain is linked to either?sn-1 or?sn-2 position and the phosphate group is connected to the?sn-3 position. The hydroxyl group is linked to the remaining?sn-1 or?sn-2?position.

• Biochem/physiol Actions

  Lysophosphatidic?acid (LPA) is a signaling molecule and alters various cellular responses through G protein-coupled receptors (GPCRs). It stimulates smooth muscle contraction, cytoskeleton rearrangement and chemotaxis. LPA is also involved in inducing neurotransmitter release, cell proliferation, platelet aggregation and Ca2+ mobilization. Increased levels of LPA in human plasma leads to ovarian cancer and atherosclerosis. LPA acts as a potential biomarker for ovarian cancer.

1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt) 生産企業

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