(7S)-3',4',6,8-テトラヒドロ-6',7'-ジメトキシ-2'-メチル-6-メチレンスピロ[7H-インデノ[4,5-d]-1,3-ジオキソール-7,1'(2'H)-イソキノリン]

(7S)-3',4',6,8-テトラヒドロ-6',7'-ジメトキシ-2'-メチル-6-メチレンスピロ[7H-インデノ[4,5-d]-1,3-ジオキソール-7,1'(2'H)-イソキノリン] 化学特性,用途語,生産方法

• 説明

  Corydalis ochotensis yields this alkaloid as an amorphous yellow-brown substance furnishing a crystalline methiodide, m.p. 225°C (dec.); [αl ²² _D + 49.2° (c 0.2, MeOH). The ultraviolet spectrum of the free base in MeOH has two absorption maxima at 226 and 287 mJi. When hydrogenated over Pd-C it yields a non_x0002_crystalline dihydro derivative with [α] ²² _D+ 112°. The dihydromethine is, however, crystalline, with m.p. 92°C.

• 参考文献

  Manske., Can. J. Res., 16B, 81 (1938)
  Manske., ibid, 18B, 75 (1940)McLean, Mei-Sie Lin., Tetrahedron Lett., 3819 (1964)
  Synthesis: McLean, Mei-Sie Lin, Whelan., Tetrahedron Lett., 2425 (1968)
  Irie, Kishimoto, Uyeo., J. Chern. Soc., C, 3051 (1968)